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When a vivacious, young escort, Shannan Gilbert, vanishes on Long Island in 2010, her disappearance leads police to discover the bodies of 10 other victims buried by a serial killer. The discovery unleashes a wave of secrets, suspects, recriminations and conspiracy theories.

The discovery of the bodies of four women in Gilgo, New York, is just the beginning. Authorities believe the Long Island Serial Killer may be responsible for up to 17 deaths over a 24-year period. Investigators uncover multiple suspects and shocking theories as they race to capture this prolific killer before he strikes again.

In 2011, a 10-month-old baby girl goes missing from her home in Kansas City, Missouri. The family fears she has been kidnapped by a drifter, only to be accused by the police for being responsible. As the case gains national attention, reputations are ruined, relationships are broken and the fate of a child is left hanging in the balance.

In 1991, outgoing Jackie Galloway is found strangled and bound with ritualistic knots. Police investigate suspects in her inner circle, but are shocked when a chance encounter with a prowler leads them to discover the murderer is a budding serial killer.

In 1981, a mother and three teens are murdered in the remote town of Keddie, California. Despite a trail of suspects and illicit activity, no one is ever brought to justice. However, recently discovered evidence may be the key to finally cracking the case.

In 2012, hikers in Hollywood Hills, California, discover the severed head of Hervey Medellin, a retired flight clerk. The cast of suspects includes former lovers, drug cartels and a murderous porn star. The case becomes a movie-worthy tale of lust, greed and butchery.

In 1995, bright 16-year-old student Adrianne Jones is found shot to death in Grand Prairie, Texas. A model student and athlete, there seems to be no reason for her death, and police have no strong suspects. However, nine months later, a game of truth-or-dare leads to a startling confession.

In one of the most famous unsolved cases in recent memory, six-year-old beauty-queen JonBenet Ramsey is found murdered in her Boulder, Colorado, home in 1996. Investigators try to unravel if she was killed in a kidnapping gone wrong, by a home intruder or by one of her own family.

A lone survivor is the only witness who can help police track down a serial killer known as the Grim Sleeper, who preys on women in South-Central Los Angeles. After decades of searching, police hone in on an unlikely suspect.

In 2004, the small town of Craig, Alaska, is shocked when the charred body of beloved mother and wife Lauri Waterman is discovered. Police have no leads until they question a former boyfriend of Lauri's daughter, who claims he knows who killed Lauri.

An army surgeon, Jeffrey MacDonald, is the lone survivor of a brutal 1970 home invasion that claims the lives of his wife and daughters. However, authorities doubt his story of murderous hippies, leading to a nearly 50-year battle, full of twists and turns.