Grey's Anatomy

Guy Fieri rolls out for some classic American grub, discovering the secret recipe of the cabrito burger at a gourmet roadside shack in Tarpley, Texas; flipping the perfect over-easy egg in a Kansas diner; and stumbling upon a Mediterranean mecca on the long desert highway between Los Angeles and Las Vegas.

In Cambridge, Mass., Guy visits a Greek joint serving lamb, and in Nashville, Tenn., he goes to a Cajun joint known for its classic bayou crawfish boil. Then in Maryland, Guy stops at a restaurant cranking out American standards.

Guy Fieri's up early and rolling out to some of America's greatest breakfast joints: Digging into the famous "Garbage Plate" at Franks Diner in Kenosha, Wis. (brought to its location by a team of horses in 1926); checkin' out the Chili Verde omelet at The Coffee Cup in Boulder City, Nev., and the "great for what ails you" John Wayne Breakfast at the Gaffey Street Diner in San Pedro, Calif.

Guy Fieri's on the hunt for the secrets of some of the best barbecue in America: Louie Meuller's in Taylor, Texas, for the surprising secret behind their world famous brisket; Barbecue King in Charlotte, N.C., where carhops bring pulled pork and barbecue fried chicken to your car, and Baby Blues in Venice, Calif., where they're fresh roasting hot peppers for a sauce they call Triple-X.

This trip Guy's heading out for big flavor.

Guy Fieri chases down some of the best of America's signature dish at three classic burger joints: Hackney's in Chicago, where they serve them inside out; The Squeeze Inn in Sacramento, Calif., where a third-pound burger is topped with a quarter pound of cheese and steamed with ice to create a huge, messy delight; and The Triple X Drive-In in West Lafayette, Ind., where they've created a burger made with peanut butter.

Guy Fieri stops in for some one-of-a-kind specials: The Red Arrow Diner in Manchester, N.H., where they're cooking homemade Twinkies and have been baking 20 kinds of pie since 1922; Voulas Cafe in Seattle for their signature "Hobo scramble" breakfast; and Hank's Creekside in Santa Rosa, Calif., where they serve every kind of "Benedict" imaginable.

Guy Fieri rolls out to some legendary joints that take visitors back in time, like Taylor's Automatic Refresher in St. Helena, Calif., an original 1940s take-out only burger joint where nothing has changed -- except the choice of burgers now includes Ahi Tuna. At Southside Soda Shop and Diner in Goshen, Ind., it's a total 1960s experience with the special homemade chili over spaghetti in a parfait glass. And Byways Cafe in Portland, where the red vinyl booths and checkered floor keep it feeling like the 1950s, and they make their own corned beef hash and key lime pie.

This trip Guy's pulling in for a world of flavor.

Guy Fieri rolls in to the Beacon Drive-in in Spartanburg, S.C., where the specialty is the A-Plenty, a meal or sandwich covered in French fries and homemade onion rings.

This trip Guy's rolling out for a Triple-D take on chicken.