The UnXplained

Charmaine is a woman from Trinidad suffering from one of the most extreme case of neurofibromatosis ever recorded. Tumors cover every inch of her body and threaten her life by obstructing her ability to breathe and swallow. Without life-saving surgery, her growing tumors threaten her ability to eat and breathe.

Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist. As the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

A massive tumor on Tim's neck continues to grow at an alarming rate, but doctors fear that removing it could leave him paralyzed.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor. Also, Amy has let the tumor on her back grow for more than 17 years. After finally making the decision to remove it, she learns that now it might be too late.

The bulbous and veiny tumor growing from Jennifer's stomach is now threatening her relationship with her long-time boyfriend. With his family by his side, 15-year-old Marcelo travels from Angola to Los Angeles to have a massive neck tumor removed, but the dangers of an unsuccessful operation may be more than surgeons are willing to risk.

The enormous mass on the back of Arlin's neck and head constantly oozes fluids, but the surgery to rectify it may prove to be too challenging. A tumor spreading on Renae's shoulder and back has caused her to retreat from the public's eye, impacting her job as the care pastor in her church.